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Regenerative Stem Cell Therapy

Using Your Own Stem Cells to Relieve Your Pain and Repair Your Body

What is Stem Cell Therapy?

Stem cell therapyStem Cell Therapy, is part of a broader, emerging and exciting area of Medicine called “Regenerative Medicine.”   Stem Cell Therapy uses the most potent cells (stem cells) from bone marrow to repair or rebuild injured or degenerated body tissue such as joints, muscles, tendons or ligaments.   The bone marrow is rich in stem cells, growth factors and cell signaling substances.  Stem cells are drawn in a painless way from the pelvic bone and then is injected, along with your concentrated platelet blood product rich in growth factors (Platelet Rich Plasma) into the painful body part, usually using ultrasound guidance for better visualization.  Your Platelet Rich Plasma comes from a simple blood draw, which we spin to separate and extract the platelet rich component.  Sometimes we inject fat with this mixture as it can activate injected stem cells and create a healthy environment for them to multiply as well as for providing a cushion.

Dr. Pearl has been trained by Dr. Joseph Purita at the National Institute of Regenrative Medicine. Dr. Purita is one of the worlds leading experts on Regenerative Medicine and Stem Cell Therapy.

What is a Stem Cell?

Stem cells are “unspecialized” cells that can develop into another type of cell that is required to repair or replace damaged tissue. They are the body’s “repairmen.” We all have stem cells because our own cells are continually dying and being replaced with new cells. Stem cells are present in bone, fat and blood, but are concentrated mostly in the bone marrow, where blood cells are made. Bone marrow (hematopoietic) stem cells usually develop to form whole blood – red blood cells, white blood cells and platelets. However, in other parts of the body, when exposed to the right growth factors and signaled by neighboring cells, these stem cells can develop into other cells, such as bone, cartilage, tendon and ligaments and therefore, can “regenerate” body tissue. They can also reproduce to make more stem cells for more even healing.

stem cell treatment for morton's neuroma

So, why does our body not heal itself?

Degeneration often occurs in areas of the body where there is a low blood supply and oxygen level such as in the intermetatarsal spaces where Morton’s neuromas occur. The body’s stem cells have difficulty reaching these areas of low blood supply and oxygen for  normal cell signaling to take place in healing and regeneration. Stem Cell Therapy provides the right cells, growth factors and cellular environment in the right location to promote healing and regrowth in a body area where blood flow and stem cells could otherwise not easily reach, like the intermetatarsal spaces where Morton’s neuromas occur.

Is Stem Cell Therapy right for you?

Although Stem Cell Therapy is considered by some folks to be experimental, various research studies show that regenerative stem cell therapy and platelet rich plasma can provide excellent relief from musculoskeletal pain and ongoing inflammation which occurs in cases of difficult to treat Morton’s neuroma and Plantar Fasciitis.

We believe that Stem Cell Therapy and Plasma Rich Platelet injections should be utilized before any surgical attempt is made especially if you are considering redo surgery in cases of ongoing pain after initial Morton’s neuroma surgery or after Plantar Fasciitis surgery.

What is the process for Stem Cell Therapy?

Stem cell therapy for MortonsAlthough stem cells are naturally present in almost all the tissues in varying degrees, the highest concentration occurs in the bone marrow. Stem cells are gathered by aspirating (removing through suction) bone marrow from the back of a patient’s pelvis. This substance is removed from the patient’s pelvis with a tiny needle. Since the patient is given a local anesthetic, only minimal discomfort results from the procedure.

In most cases, 2 oz. (60 cc) of bone marrow aspirate is required. The aspirate includes platelets, mesenchymal stem cells, and other kinds of stem cells used in adult stem cell therapy. After aspiration, the stem cell tissue is separated from non-useful substances and cells via multiple filtration techniques. The bone marrow is placed inside a special container, which in turn is placed into a machine known as a centrifuge. The centrifuge spins the material at a high rate of speed, and this process separates the platelets and stem cells from the remainder of the blood products. It is this concentration of bone marrow—called BMAC, or bone marrow aspiration concentrate that is injected to the site of tissue damage or injury. We use ultrasound and nerve stimulator guidance to increase the accuracy of administration

Once introduced, the platelets then release signal proteins and growth factors which activate the stem cells to divide rapidly. Stem cells by themselves are unable to repair the injured area. These cells have to be properly directed, and platelets perform this function. In effect, stem cells are construction workers and the platelets are their supervisors. Once they are activated, these stem cells perform a variety of valuable functions. Apart from repairing damage to the injured areas, they help damaged cells repair themselves and participate in the repairing process.

Stem Cell Therapy can:

  • Repair tissue that is too damaged to heal on its own
  • Regenerate tissue that is missing (ex.: cartilage in arthritic joints)
  • Provide a renewable source of replacement cells and tissues
  • Release cytokines which are chemical messenger like compounds which further promote the regeneration process.
  • Provide hyaluronic acid which helps in restoring mobility and flexibility.

Stem cells are now being studied for use in a wide range of conditions, from diabetes, to heart disease, to musculoskeletal disorders, to neurological disorders. Investigators believe that breakthrough therapeutic tools like stem cell therapy can be used to manage degenerative musculoskeletal disorders such as arthritis, plantar fasciitis, Morton neuroma and other disabling conditions.

What are some other conditions for which Stem Cell Therapy can be used?

Serious or severe foot and ankle musculoskeletal foot injuries are excellent candidates for stem cell therapy. Besides Morton neuroma and plantar fasciitis; other indications of using stem cell therapy are:

  • Severe sports related injuries
  • Genetic factors or hereditary musculoskeletal conditions
  • Foot and ankle overuse or abuse injuries
  • History of traumatic accidents
  • Osteoarthritis
  • Osteonecrosis
  • Fractures and other traumatic injuries

Why choose us for your stem cell treatment?

stem cell treatment
Morton's Neuroma Stem Cell Therapy

Stem Cell Therapy Frequently Asked Questions (FAQ’s):

Why choose us for your stem cell treatment?

Morton's neuroma stem cell

What types of problems can be treated?

We believe that Stem Cell Therapy and Plasma Rich Platelet injections should be utilized before any surgical attempt is made especially if you are considering redo surgery in cases of ongoing pain after initial Morton’s neuroma surgery or after Plantar Fasciitis surgery.

Who is not a candidate for Stem Cell Therapy or PRP injections?
  1. Patients with active cancers and/or infections.
  2. If bone marrow cells are to be utilized and a patient had a history of a bone marrow derived type of cancer (i.e. lymphoma), this would be considered a relative contra-indication.  However, many times those patients can utilize PRP injections and fat cells, but the ultimate decision maker should be their oncologist.
How long does Stem Cell Treatment take?

While the bone marrow draw only takes a few minures, the total procedure may take up to 2 to 3 hours.

How much does Stem Cell Therapy Cost? Is it covered by insurance?

One of the most common questions that people ask is “how much does Stem Cell Therapy cost?”

These procedures are NOT covered by health insurance plans. But, with financing, many patients can get their painful joints and back treated for a minimum investment. There are a variety of different financing options available, and we can help you find the best one for you.

The total cost will depend on the:

  • severity and extent of your medical condition,
  • how long you have had this problem,
  • number of joints/areas that need to be treated, and
  • how many types of cells are necessary to achieve the results you desire

Each patient’s medical requirement is unique and all our procedures are individualized just for you. Therefore a consultation with our Medical Director (over the phone or face-to-face) is needed to decide your best treatment option and to give you an estimate of the exact cost to you.

To see if you qualify for financing, click the logo below:

stem cell finance

 

What are the Potential Benefits of Treatment?

Patients may see a significant improvement in their symptoms. This may eliminate the need for more aggressive treatments such as long term medication or surgery, as well as a potential remarkable return of function…

Does Stem Cell Therapy hurt?

There may be some pressure at the injection site, but the process is fairly quick. You will be giving a numbing agent to help maintain comfort during your treatment.

How do I prepare for Stem Cell Therapy?

Do not take over-the-counter medications that can thin your blood (aspirin, Motrin, Aleve Advil, Naproxen, etc.). Drink as much water as possible on the day of your injection. Arrange for someone to drive you home after treatment.

What should I expect following Stem Cell Therapy?

You will be numb for an hour or two at the injection site, and may experience much more soreness than usual for the first few days after treatment. After the numbness wears off, refrain from any activities that increase your discomfort, and refrain from taking anti-inflammatory medications for at least four weeks after treatment. Control your pain with acetaminophen (Tylenol®) or medications that your doctor prescribes. Use ice sparingly, for up to 20 minutes at a time every two to three hours. Resume any physical therapy regimen about a week after treatment. Your recovery time will depend on the specific condition that is being treated. In all cases, the stem cell injections at the site of your injury will need time to grow your new cells. As the regeneration of new cells proceeds, you should notice a gradual improvement in your level of discomfort, and in your range of motion.

What is the success rate?

The great majority of patients who responded said that they were satisfied with their treatment and would do it again.  More detailed data from early patients is being collected.

According to the National Institute of Regenerative Medicine, knee and hip patients with severe arthritis who were told they needed a joint replacement surgery have responded as follows:

  • The great majority of knee patients reported more than 50% relief of symptoms.
  • The great majority of hip patients reported more than 50% relief.
What else should I know about Stem Cell Therapy?
  • A lot of people are concerned about the efficacy, reliability and safety of stem cell procedure. Stem cell therapy is safe since your own stem cells (autologous) are used. This minimizes the risk of reaction, adverse effects or rejection.
  • Stem cell therapy has been statistically proven to aid in the regeneration of meniscal tissues and articular cartilage. In addition, these cells also help in reducing the subchondral and osteophytic remodeling. When used in combination with platelet rich plasma therapy, the efficacy of combination is compared with the bone grafting procedure.
  • According to a one study, in which stem cell therapy was administered after Achilles tendon surgery, investigators reported remarkable improvement in the process of the healing and recovery of the Achilles tendon. The positive effects were also reported in the surrounding connective tissue elements.

References:

  • Davidson, J., & Jayaraman, S. (2011). Guided interventions in musculoskeletal ultrasound: what’s the evidence?. Clinical radiology, 66(2), 140-152.
  • Hanselman, A. E., Lalli, T. A., & Santrock, R. D. (2015). Topical Review Use of Fetal Tissue in Foot and Ankle Surgery. Foot & ankle specialist, 1938640015578513.
  • Finnoff, J. T., Hall, M. M., Adams, E., Berkoff, D., Concoff, A. L., Dexter, W., & Smith, J. (2015). American Medical Society for Sports Medicine Position Statement: Interventional Musculoskeletal Ultrasound in Sports Medicine. Clinical Journal of Sport Medicine, 25(1), 6-22.

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Janet-Pearl-MD

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